EPS workshop “Single-cell Omics in plants”
Gene expression is regulated in response to developmental and environmental cues and enables organisms to respond appropriately to internal and external signals. Because gene-regulatory programs are often different across cell types, cell-specific transcriptional responses are typically not observed when profiling gene expression in whole organs or tissues. However, emerging single-cell genomic technologies, including transcriptomics, are being used to characterize gene expression dynamics at unprecedented resolution. In addition to profiling cell-type specific responses in gene expression, single-cell transcriptomics is being used to discover new cell types, track cellular differentiation and predict gene-regulatory networks. Although single-cell transcriptomics techniques are typically more challenging in plants (e.g. due to presence of cell walls), recent technological advances are revolutionizing how we characterize gene regulation.
In this two-day workshop, a combination of external and local speakers will present various topics related to single-cell transcriptomics in plants. Presentations will cover the latest technologies and computational approaches employed during single-cell transcriptomics experiments, as well as how these single-cell approaches are being used to address both fundamental and applied research questions in plants. During the computer practicals, participants will also learn how to analyze and visualize single-cell transcriptomic datasets. Altogether, we aim for this course to help plant researchers design, execute and analyze single-cell transcriptomics experiments, and explore up-and-coming single-cell genomic applications.
Date: February 20th – 21st February 2025
Location: Campus, Wageningen University and Research
Fee:
210 € for PhD candidates of EPS with an accepted TSP
315 € for postdocs registered with EPS
420€ for all other employees at the Universities
840 € Industry
Registration: open
Confirmed speakers:
- Michael Nodine (WUR),
- Leonardo Jo (WUR)
- Jose Lozano (WUR)
- Carolin Grones (WUR)
- Kelvin Adema (WUR)
- Michael Schon (WUR)
- Jian Xu (RU)
- Victoria Mironova (RU)
- Aki Minoda (RU)
- Petra van Bergeijk (Keygene)
Organizers: Victoria Mironova and Michael Nodine and EPS
Content: Lectures and computer practicals/ invidual sessions incl demonstrations (in parallel sessions)
Computer practicals:
- Single cell data preprocessing. Michael Schon (WUR)
- Seurat: from counts to clusters. Victoria Mironova (WUR)
- From clusters to marker genes. Fabienne Giddink (RU)
- Single cell data integration. Victoria Mironova (RU)
Demonstrations:
- Singleron
- BMKGENE
Sponsors
We proudly announce our Gold Sponsor :
Thursday, February 20, 2025 through February 21
00:00 - 23:59
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